Monday, Apr. 26, 1993

The Fungus Among Us

They don't look like you or me, and there is something vegetable-like about their life-style, but toadstools, molds and yeast may be far more closely related to humans than to plants. That's the conclusion of a report in Science magazine comparing fungi to a variety of organisms, from protozoans to frogs. Rather than studying how the organisms live or reproduce, the researchers relied on genetic analysis. Examining one gene as it mutated across 22 species, they found evidence that humans and fungi, despite obvious differences, have a single ancestor: a one-celled creature that branched away from the plant kingdom a billion years ago.

The findings may explain why fungal infections are so hard to control, since drugs that attack fungi often hurt people as well. And conscientious vegetarians may be discombobulated: Are mushrooms one more thing they can't eat?