Abstract

Immunotherapeutic agents are used in treatment of primary immunodeficiencies as well as those immune system aberrations resulting from other diseases. A number of natural and synthetic agents have been discovered that can modulate components of the immune system. Furthermore, cytokines, such as interleukins, and immune cells having specific markers, such as antibodies, continue to be defined, leading to a complex although incomplete picture of immune responses. The immune system and its responses are discussed.

Immunomodulators that play a role in the treatment of acquired immune deficiency syndrome as well as those used in therapy for rheumatoid arthritis, an autoimmune dysfunction, are described. Immunosuppressants used in anticancer therapy and organ transplants are presented.